Supporting Paediatric Liver & Intestinal Transplantation

Our aim is to support children and young people with liver disease and those requiring liver and/or intestinal transplantation

What We do

CHILDREN GET LIVER DISEASE TOO! 1 in 1000 children born in the UK develop liver disease Twenty years ago most children died, usually before their first birthday. Today, advances in Diagnosis, Molecular Genetics, New Drug Therapy, Liver Transplantation means that we can save children with liver disease.

SPLIT Supports children with liver disease and their families through:

  • Financial support for needy families in crisis
  • Information and education for families, professionals and the public
  • Research into the causes of liver disease and how best to treat it

Harriet’s Story

Harriet was born with a rare liver disease, biliary atresia, which causes the bile to be trapped into the liver poisoning the whole body. She nearly died but now after successful transplantation, Harriet is enjoying life like other healthy children of her age.

baby, boy, child

How You Can Support Us

How You Can Make a Donation
You can make a gift to SPLIT by sending us a cheque made payable to SPLIT Click here to download charity information leaflet
Gift Aid Declaration
As part of the Gift Aid Scheme it is now possible for charities to reclaim the tax you pay on your donation if you are a basic rate taxpayer. If you complete the Gift Aid declaration it means that for every £1 you give, SPLIT can claim an extra 28p from the taxman at current tax rates, provided you pay enough tax to cover the amount reclaimed. It won’t cost you a penny extra and if you pay tax at the higher rate, you can claim further tax relief on your self assessment tax return. Click here to download the Gift Aid form

Research & Education

SPLIT has funded the following research projects:

  • Identification of the causative disease gene(s) for the inherited paediatric liver diseases asphyxiating thoracic dystrophy (ATD) (Dr Jane Hartley, Clinical Research Fellow)
  • Conjugated Bilirubin Study (Dr Mark Viant)
  • Development of rapid microarray-based genetic diagnosis in children presenting with liver disease (Dr Paul Gissen, GSK Clinical Scientist)
  • Faecal calprotectin as a non-invasive marker of rejection following liver and bowel transplantation (Dr Girish Gupte, Consultantl)

Our most recently completed research application:

Neuro-physiological impact of deprivation of polyunsaturated fatty acids (PUFAs) in infants with liver disease before and after liver transplantation (Dr Sue Beath, Consultant Paediatric Hepatologist).

Would you like to raise some funds for us? Your funds will help SPLIT to continue their research into the liver disease. With your help, we can make a difference to the lives of many children and young people affected by liver disease and those requiring liver and/or intestinal transplantatiion.

For further enquiries please email: Fundraising Packs We now have the following fundraising packs for schools available: If you would like to order some packs please email: